ScienceDaily Health Headlines
for Tuesday, January 5, 2010
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Obesity now poses as great a threat to quality of life as smoking (January 5, 2010) -- As the US population becomes increasingly obese while smoking rates continue to decline, obesity has become an equal, if not greater, contributor to the burden of disease and shortening of healthy life in comparison to smoking. In a new study, researchers calculate that the Quality-Adjusted Life Years (QALYs) lost due to obesity is now equal to, if not greater than, those lost due to smoking, both modifiable risk factors. ... > full story
Refusing chickenpox vaccine associated with increased risk of disease (January 5, 2010) -- Children whose parents refuse the varicella (chickenpox) vaccine appear more likely to develop the disease, according to a new study. ... > full story
Can Supplements Help People with Diabetes Avoid Retinopathy? (January 5, 2010) -- In theory, Vitamins C and E and magnesium could help prevent or limit diabetic retinopathy (DR), a potentially blinding disease, since each nutrient causes the body to respond in ways that alter retinopathy mechanisms. ... > full story
Nurse home visitation program reduces girls' potential criminality later in life (January 5, 2010) -- Girls whose mothers were visited at home by nurses during pregnancy and the children's infancy appear less likely to enter the criminal justice system by age 19, according to a new study. ... > full story
Scans Show Learning 'Sculpts' The Brain's Connections (January 5, 2010) -- Spontaneous brain activity formerly thought to be "white noise" measurably changes after a person learns a new task, researchers have shown. Scientists also report that the degree of change reflects how well subjects have learned to perform the task. ... > full story
Exercise helps patients with peripheral artery disease (January 5, 2010) -- Peripheral artery disease affects 5 million individuals in the US and is the leading cause of limb amputations. Doctors have long considered exercise to be the single best therapy for PAD, and now a new study helps explain why. ... > full story
Highway Barriers Stifle Sound, Sight, and Soot (January 5, 2010) -- Highway barriers erected along roadways to block the sound and sight of traffic for the adjoining neighborhoods may also be reducing the amount of pollutants, such as soot from diesel exhaust, reaching area residents. ... > full story
How precursors of gene-regulating small RNAs are sorted by cellular machinery (January 5, 2010) -- A team of scientists has determined a hierarchical set of criteria that explain how the molecular precursors of gene-regulating small RNAs are sorted by the cellular machinery. ... > full story
Pain management failing as fears of prescription drug abuse rise (January 5, 2010) -- Millions of Americans with significant or chronic pain associated with their medical problems are being under-treated as physicians increasingly fail to provide comprehensive pain treatment -- either due to inadequate training, personal biases or fear of prescription drug abuse. ... > full story
Discovery aims to correct cellular defects leading to diabetes (January 4, 2010) -- A recent discovery may change the perception and treatment of diabetes. That's because scientists have moved closer toward correcting the root cause of the disease rather than managing its symptoms. Specifically researchers identified a protein and its antioxidant product that both prevent the death and promote the growth of cells which produce and release insulin in the pancreas. ... > full story
Protection of organic products taken to next level (January 4, 2010) -- Ready-to-eat, organic processed pork products look similar to conventionally cured meats. The organic versions have become popular among consumers as processors work to meet the demand. Although the natural and organic processed meat products are manufactured to simulate traditionally cured meat products as closely as possible, they're not exactly alike. ... > full story
Bardet-Biedl syndrome proteins shown to run an export business that protects cilia (January 4, 2010) -- A protein complex mutated in human disease removes excess signaling molecules to prevent them from damaging cilia, say researchers. ... > full story
Licorice root: Trip to the candy store might help ward off rare, but deadly infections (January 4, 2010) -- As it turns out, children were not the only ones with visions of sugar plums dancing in their heads over this past holiday season. In a new study, scientists show how a compound from licorice root might be an effective tool in battling life-threatening, antibiotic-resistant infections resulting from severe burns. ... > full story
Angina In The Legs? Time To Alert Patients And Physicians (January 4, 2010) -- Researchers recommend that people over age 40 be screened for peripheral artery disease (PAD), which puts people at high risk for serious medical complications including heart disease, stroke and possible lower limb amputation. ... > full story
Pandemic toolkit offers flu with a view (January 4, 2010) -- As communities brace for rising wintertime influenza cases, scientists are developing a mathematical and visual analytic toolkit to help health officials quickly analyze pandemics and craft better response strategies. ... > full story
Vitamin C 'cures' mice with accelerated aging disease (January 4, 2010) -- New research suggests that treatments for disorders that cause accelerated aging, particularly Werner's syndrome, might come straight from the family medicine chest. In their study, a team of Canadian scientists shows that vitamin C stops and even reverses accelerated aging in a mouse model of Werner's syndrome, but the discovery may also be applicable to other progeroid syndromes. ... > full story
Finally, an excuse for pregnant women to eat bacon and eggs (January 4, 2010) -- If you're pregnant and looking for an excuse to eat bacon and eggs, now you've got one: new research shows that choline plays a critical role in helping fetal brains develop regions associated with memory. Choline is found in meats, including pork, as well as chicken eggs. ... > full story
PSA value at 2 years post-treatment can predict long-term survival in prostate cancer patients (January 4, 2010) -- Prostate cancer patients who have a prostate-specific antigen value of less than or equal to 1.5 at two years after external beam radiation therapy are less likely to have a cancer recurrence and cancer-related death, according to a new study. ... > full story
Experimental drug shows promise against brain, prostate cancers (January 4, 2010) -- An experimental drug currently being tested against breast and lung cancer shows promise in fighting the brain cancer glioblastoma and prostate cancer, researchers have found in two preclinical studies. ... > full story
Chronic sinusitis patients experience improved quality of life after endoscopic sinus surgery (January 4, 2010) -- Upwards of 76 percent of patients with chronic rhinosinusitis experienced significant quality of life improvements after undergoing endoscopic sinus surgery, according to new research. ... > full story
Demonstration of pH-regulating protein (January 4, 2010) -- Researchers have identified the protein mechanism that senses bicarbonate fluctuations and adjusts blood pH levels. Scientists have now achieved the first demonstration of the process in a whole animal. The researchers found that the protein adenylyl cyclase sensed and then regulated the pH blood levels in a dogfish shark following feeding. ... > full story
Severe asymptomatic heart disease may accompany narrowing in leg arteries (January 4, 2010) -- Results of a randomized, controlled clinical trial reveal that one in five patients with narrowing or blockage in arteries that supply blood to the legs and other parts of the body also have significant but silent coronary artery disease. ... > full story
Breast cancer survival improves if Herceptin is used with chemotherapy (January 4, 2010) -- Using Herceptin with chemotherapy, instead of after, clearly improves treatment of women with HER2+ breast cancer, and should be the new standard of care, says a researcher. ... > full story
How you remember dance steps depends on culture: I think step to the left, you think step to the east (January 4, 2010) -- Even the way people remember dance moves depends on the culture they come from, according to a new article. Whereas a German or other Westerner might think in terms of "step to the right, step to the left," a nomadic hunter-gatherer from Namibia might think something more like "step to the east, step to the west." ... > full story
Acute stress leaves epigenetic marks on the hippocampus (January 4, 2010) -- In trying to explain psychiatric disorders, genes simply cannot tell the whole story. The real answers are in the interaction of genes and the environment. Post-traumatic stress disorder requires some trauma, for instance, and people, for the most part, aren't born depressed. Now research has revealed one mechanism by which a stressful experience changes the way that genes are expressed in the rat brain. The discovery of "epigenetic" regulation of genes in the brain is helping change the way scientists think about psychiatric disorders and could open new avenues to treatment. ... > full story
'Notch'ing up a role in the multisystem disease tuberous sclerosis complex (January 4, 2010) -- Two independent teams of researchers have identified a role for enhanced activation of the signaling protein Notch in tumors characterized by inactivation of either the TSC1 or the TSC2 protein. These data provide a rationale for testing whether Notch inhibitors are of benefit to those with TSC-associated tumors. ... > full story
Low-income women four times more likely to report fair or poor health (January 4, 2010) -- Low-income women are four times more likely to report fair or poor health, and nearly twice as likely to report a health condition that limits one or more of the basic physical activities, according to a new policy brief. They also experience inadequate access to health insurance and health care to a far greater degree than higher-income women, the study found. ... > full story
Psoriasis: Effects don’t always stop with the skin (January 4, 2010) -- Psoriasis, a chronic disease that causes red, raised patches of skin, is increasingly seen as a systemic disease with links to arthritis and cardiovascular disease. ... > full story
How ubiquitin chains are added to cell-cycle proteins: May lead to targeted cancer therapies (January 4, 2010) -- Researchers have been able to view in detail, and for the first time, the previously mysterious process by which long chains of a protein called ubiquitin are added by enzymes called ubiquitin ligases to proteins that control the cell cycle. Ubiquitin chains tag target proteins for destruction by protein-degrading complexes in the cell. ... > full story
Osteopontin contributes to allergic contact dermatitis (January 4, 2010) -- Researchers in Germany have discovered that osteopontin (OPN) contributes to allergic contact dermatitis. ... > full story
Increased risk of death, stroke in postmenopausal women taking antidepressants, study finds (January 4, 2010) -- Women participating in the Women's Health Initiative study who reported taking an antidepressant drug had a small but statistically significant increase in the risk of stroke and of death compared with participants not taking antidepressants. The authors of the study note that their findings are not conclusive but may signify a need for additional attention to patients' cardiovascular risk factors. ... > full story
Multitasking may be Achilles heel for hepatitis C (January 4, 2010) -- Despite its tiny genome, the hepatitis C virus packs a mean punch. The virus is a microcosm of efficiency, and each of its amino acids plays multiple roles in its survival and ability to sidestep attack. But new research suggests that this fancy footwork and multitasking could be the key to bringing down the virus. The work, which focuses on a once-ignored protein, provides insights on how drug therapy for sufferers of the disease might be improved. ... > full story
Scientists visualize how a vital hepatitis C virus protein moves along its nucleic acid substrate (January 4, 2010) -- By taking three conformational snapshots of a hepatitis C virus motor protein in association with its substrate, researchers have provided the first structural explanation of how a representative superfamily 2 helicase moves unidirectionally along nucleic acid, suggesting new ways that drug designers could block virus replication. ... > full story
Inflammatory mediator regulates diarrhea in inflammatory bowel disease (January 4, 2010) -- Researchers have discovered that activation of NF-kappaB, an inflammatory mediator, results in diarrhea in inflammatory bowel disease (IBD). ... > full story
Three new alkaloids found in winter snowdrop plants (January 4, 2010) -- Scientists have identified 17 bioactive compounds in winter snowdrops, the earliest flowering plants in Europe. Out of the alkaloids identified, three are new to science and belong to a group with potential applications in treating malaria and Alzheimer's disease. ... > full story
Pharmacists improve care of diabetics while cutting costs, research shows (January 4, 2010) -- The role of pharmacists hasn't received much attention in the debate on the cost of health care. But national and regional studies show that when pharmacists directly participate in patient care, they significantly reduce treatment costs and improve outcomes. ... > full story
Mutant gene lessens devastation of flesh-eating bacteria (January 3, 2010) -- Scientists recently discovered a simple gene mutation that decreases the chance people will get a flesh-eating disease called necrotizing fasciitis. Further, they proved that inactivating this section of the gene lessens the devastating disease in humans. ... > full story
Carbon nanotubes show promise for high-speed genetic sequencing (January 3, 2010) -- Scientists have demonstrated the potential of a new DNA sequencing method in which a single-stranded ribbon of DNA is threaded through a carbon nanotube. ... > full story
Alzheimer's: How amyloid beta reduces plasticity related to synaptic signaling (January 3, 2010) -- The early stages of Alzheimer's disease are thought to occur at the synapse, since synapse loss is associated with memory dysfunction. Evidence suggests that amyloid beta plays an important role in early synaptic failure, but little has been understood about amyloid beta's effect on the plasticity of dendritic spines. ... > full story
Two proteins act as molecular tailors in DNA repair (January 3, 2010) -- Every day tiny segments of our DNA are chipped or fragmented or get stuck together when they should really be pulled apart. But what our genome necessarily lacks in stability it makes up for with a phalanx of guards that monitor and repair the damage. ... > full story
Changing Behavior Helps Patients Take Medication As Prescribed (January 3, 2010) -- Researchers found that applying behavior changing strategies, such as using pill boxes or reducing the number of daily doses, can improve patients' abilities to take their medications as required. ... > full story
'Lifeless' prions capable of evolutionary change and adaptation (January 3, 2010) -- Scientists have determined for the first time that prions, bits of infectious protein devoid of DNA or RNA that can cause fatal neurodegenerative disease, are capable of Darwinian evolution. ... > full story
Unusual protein modification involved in muscular dystrophy, cancer (January 3, 2010) -- With the discovery of a new type of chemical modification on an important muscle protein, a new study improves understanding of certain muscular dystrophies and could potentially lead to new treatments for the conditions. ... > full story
Physiologic factors linked to image quality of multidetector computed tomography scans (January 3, 2010) -- The image quality of multidetector computed tomography scans, used for the noninvasive detection of coronary artery disease, can be significantly affected by patient characteristics such as ethnicity, body mass index and heart rate, according to a new study. ... > full story
Telephone Depression Program Offers Benefits At A Moderate Cost (January 3, 2010) -- Patients who participate in a structured telephone program to manage their depression appear to experience significant benefits and only a moderate increase in health care costs when compared with those who receive usual care, according to a new report. ... > full story
Scientists identify DNA that regulates antibody production (January 3, 2010) -- Performance enhancers are the currency of a competitive society. But there's one that we have always had: For millions of years, segments of our DNA have improved the performance of our genome, revving up protein production at those times we need it most. New research now show that these genome enhancers regulate how our bodies make germ-fighting antibodies, molecules that keep savvy viruses and bacteria at bay. ... > full story
Small changes in protein chemistry play large role in Huntington's disease (January 3, 2010) -- Investigators studying the toxic protein at the root of Huntington's disease have found that small biochemical changes to the protein have a large effect on its toxicity. These changes could be exploited or mimicked to develop a drug treatment for Huntington's. ... > full story
Molecular anchor links the two inheritable diseases Fanconi anemia and Bloom's syndrome (January 3, 2010) -- A new study establishes a molecular link that bridges two rare inherited disorders and explains why these diseases result in genetic instability. The research may lead to a better understanding of the complex mechanisms that enable cells to repair damaged DNA. ... > full story
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